File:Multidrug-resistant-tuberculosis-without-extensive-drug-resistance1.png

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Description
English: Drug resistant tuberculosis

Drug resistant tuberculosis is a form of tuberculosis that does not get better with the standard antibiotic treatment for the disease. The standard treatment for tuberculosis (also known as the first-line treatment) is typically a combination of the antibiotics: rifampicin, isoniazid, pyrazinamide and ethambutol. If tuberculosis has developed resistance against these antibiotics, it is more challenging to treat – it requires longer treatment with other drugs, which can be less effective, more toxic, or more expensive. There are two classifications of drug resistant tuberculosis: multidrug resistant tuberculosis and extensively drug resistant tuberculosis. In multidrug resistant tuberculosis, patients do not respond to treatment from the two main first-line drugs (rifampicin and isoniazid) used to treat tuberculosis.

In extensively drug resistant tuberculosis, patients meet the criteria for multidrug resistant tuberculosis, and also do not respond to treatment from any fluoroquinolone (the second-line treatment for tuberculosis), and at least one other second-line drug.
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Prevalence of MDR-TB

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4 June 2025

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