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DescriptionNecrobiotic Collagen.jpg
English: In the dermis, there is degenerate (so-called ‘necrobiotic’) collagen (arrows) bordered by an irregular inflammatory infiltrate (arrowheads) composed of histocytes, lymphocytes, and occasional plasma cells. Although this can be difficult to distinguish from other causes of so-called necrobiotic (collagenolytic) granulomas, such as granuloma annulare, the morphological features including the irregularity of the contours are quite typical for necrobiosis lipoidica.
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A case series and literature review of necrobiosis lipoidica
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