Blue nails

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2025-05-24 01:32
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Clinical

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Differential

Histology

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Variants

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Differential

Pathophysiology

Epidemiology

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Management

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Azure lunula

Blue nails, or more formally azure lunula, are characterized by a blue discoloration of the lunulae, seen in argyria and cases of hepatolenticular degeneration (Wilson's disease), also having been reported in hemoglobin M disease and hereditary acrolabial telangiectases.[1]

In Wilson's disease the blue color involves the lunula (most intense pigmentation) and fades proximally. In argyria, the nail is permanently pigmented a slate-blue color and is most evident in the lunula. Minocycline can also turn the nail plate blue-gray.[2]

See also

References

  1. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. Tosti, Antonella; Iorizzo, Matilde; Piraccini, Bianca Maria; Starace, Michela (July 2006). "The Nail in Systemic Diseases". Dermatologic Clinics. 24 (3): 341–347. doi:10.1016/j.det.2006.03.005. PMID 16798431.

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