Disseminated coccidioidomycosis
Clinical
Features
Variants
Images
Differential
Histology
Features
Variants
Images
Differential
Pathophysiology
Epidemiology
Associations
Workup
Labs
Imaging
Diagnostic criteria
Management
Treatment
Monitoring
Counseling
Other considerations
| Disseminated coccidioidomycosis | |
|---|---|
| Other names | Coccidioidal granuloma |
 | |
| Characteristic skin granulomata on the forehead. | |
| Specialty | Infectious diseases |
Disseminated coccidioidomycosis is a systemic infection caused by Coccidioides immitis. 15-20% of people with the infection develop skin lesions.[1]: 315
History of treatment
One of the earliest treatments for the disease was publicized in the New York State Journal of Medicine in 1959, in an article titled "Disseminated Coccidioidomycosis Treated with Amphotericin B". The case centered around a patient who was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. Before the introduction of Amphotericin B, disseminated coccidioidomycosis had no specific chemotherapeutic treatment. Amphotericin B, a polyene antifungal, was first trialed for this condition approximately three years earlier. Since then, multiple reports have highlighted the medication's clinical effectiveness in patients with coccidioidomycosis. [2]
See also
References
- ↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ↑ La Barbera, M.D., Salvatore A. (October 1, 1959). "Disseminated Coccidioidomycosis Treated with Amphotericin B". New York State Journal of Medicine. 59 (19): 3644.
