Delayed pressure urticaria

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2025-02-05 03:26
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Delayed pressure urticaria
SpecialtyDermatology

Delayed pressure urticaria is known as one of the more painful subsets of physical urticaria due to formed hives being deep-seated and appearing after 4–6 hours.[1]

Causes

Due to the delayed appearance of wheals, plausible causes are hard to establish; the natural course and/or clinical pattern is variable and inconclusive.[1]

Treatment

It was noted that although antihistamines and anti-inflammatory drugs such as, colchicine, sulphasalazine, dapsone, and topical steroid are advocated for in the treatment of DPU, most if not all are unsatisfactory in relieving symptoms.[1] Even a second generation antihistamine, ketotifen, was unable to efficiently and satisfactorily relieve symptoms of DPU[2]

References

  1. 1.0 1.1 1.2 Dawn, G.; Urcelay, M.; Ah-Weng, A.; O'Neill, S.M.; Douglas, W.S. (2003). "Effect of high-dose intravenous immunoglobulin in delayed pressure urticaria". British Journal of Dermatology. 149 (4). Oxford University Press: 836–840. doi:10.1046/j.1365-2133.2003.05486.x. ISSN 0007-0963. PMID 14616377.
  2. GA Vena; V. d'Argento; N. Cassano; M. Mastrolonardo (1998-07-21). "Sequential Therapy with Nimesulide and Ketotifen in Delayed Pressure Urticaria". Acta Dermato-Venereologica. 78 (4). Medical Journals Sweden AB: 304–305. doi:10.1080/000155598441981. ISSN 0001-5555. PMID 9689307.