List of cutaneous conditions associated with internal malignancy
From dermwiki
Clinical
Features
Variants
Images
Differential
Histology
Features
Variants
Images
Differential
Pathophysiology
Epidemiology
Associations
Workup
Labs
Imaging
Diagnostic criteria
Management
Treatment
Monitoring
Counseling
Other considerations
This is a list of cutaneous conditions associated with internal malignancy; skin markers of internal cancer.[1] It does not include skin infections associated with cancer or cancers that spread to skin.[1] Some have stronger associations with cancers than others.[2]
| Cutaneous condition | Internal malignancy |
|---|---|
| Erythema gyratum repens | Lung cancer |
| Hypertrichosis lanuginosa acquisita | Lung cancer |
| Paraneoplastic pemphigus | Non-Hodgkin lymphoma[nb 1] Chronic lymphocytic leukemia Castleman's disease[nb 1] Sarcoma Thymoma |
| Tripe palms | Lung cancer |
| Tripe palms with acanthosis nigricans | Stomach cancer |
| Pityriasis rotunda | Hepatocellular carcinoma |
| Migratory thrombophlebitis | Pancreatic adenocarcinoma |
| Leser–Trélat sign | Gastrointestinal adenocarcinoma |
| Acquired ichthyosis | Hodgkin disease |
| Pityriasis rotunda | Hepatocellular carcinoma |
| Paraneoplastic pigmentation | Small cell bronchial carcinoma |
| Acrokeratosis paraneoplastica | Squamous cell carcinoma of the upper respiratory or gastrointestinal
tracts |
| Necrolytic migratory erythema | Glucagon secreting
pancreatic islet cell adenoma |
| Dermatomyositis | Lung cancer in men, breast and gynaecological tumours in women and colorectal cancers in both sexes |
| Scleroderma‐like skin changes | Carcinoid syndrome |
| Paraneoplastic pemphigus | B‐cell proliferations and thymoma or thymoma‐like neoplasms; specifically Non Hodgkin's lymphoma (42%) |
| Dermatitis herpetiformis | Lymphoma |
| Porphyria cutanea tarda and variegate porphyrias | Hepatocellular Carcinoma |
| Erythroderma and exfoliative dermatitis | Mycosis fungoides or Sézary syndrome |
| Pyoderma gangrenosum | Hematological malignancy |
| Sweet syndrome | Hematological malignancy |
Footnotes
- ↑ 1.0 1.1 Non-Hodgkin lymphoma is the most common cause of paraneoplastic pemphigus in adults. Castleman's disease is the most common cause of paraneoplastic pemphigus in children.
See also
- List of target antigens in pemphigus
- List of cutaneous conditions
- List of genes mutated in cutaneous conditions
- List of cutaneous conditions caused by mutations in keratins
References
- ↑ 1.0 1.1 Wick, Mark R.; Patterson, James W. (July 2019). "Cutaneous paraneoplastic syndromes". Seminars in Diagnostic Pathology. 36 (4): 211–228. doi:10.1053/j.semdp.2019.01.001. ISSN 0740-2570. PMID 30736994.
- ↑ Fonia, Athina; Baran, Robert (2021). "Cutaneous paraneoplastic syndromes with nail involvement". In Lipner, Shari (ed.). Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics. Elsevier. pp. 175–182. ISBN 978-0-323-70924-8.
Bibliography
- Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 1-4160-2999-0.
- James, William D.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
